Ipamorelin (5MG)

Ipamorelin — a selective growth-hormone-releasing peptide (GHRP) — supplied by BioFusion as a vacuum-sealed lyophilized 5mg vial for GHRP-receptor and ghrelin-pathway research chemistry.

Research context

Ipamorelin is the standard reference peptide for selective GHRP-2-class research panels. The 5-residue Aib-His-D-2Nal-D-Phe-Lys-NH₂ structure provides high selectivity for the ghrelin/GHS-R1a receptor without significant cross-activation of cortisol or prolactin pathways — making it a frequent comparator in selectivity-mapping studies alongside CJC-1295 GHRH for combined-pathway research.

Synthesis & documentation

Produced by solid-phase peptide synthesis using Fmoc protecting-group strategy in a U.S.-based ISO 9001:2008 facility. Each lot is verified for identity (LC-MS), purity (reverse-phase HPLC-UV ≥99.0%), moisture (Karl Fischer), and counter-ion (ion chromatography). The signed Certificate of Analysis ships with every order. Non-natural residues (Aib, D-2Nal) require specific Fmoc reagent handling — see the Fmoc primer.

Storage & handling

Lyophilized Ipamorelin is stable at −20 °C for the printed shelf life. After reconstitution, the standard 14-day-at-2-8 °C reference window applies; avoid freeze-thaw cycling. The C-terminal amide is moderately base-sensitive — avoid alkaline reconstitution buffers. The reconstitution calculator handles concentration math.

Why BioFusion

The non-natural residues in Ipamorelin (Aib at position 1, D-2Nal at position 3, D-Phe at position 4) are a common point of failure for low-cost suppliers — racemization or mis-incorporation produces off-spec batches that pass mass-spec but fail receptor-binding assays. BioFusion’s lots are checked for stereochemical integrity via chiral HPLC. Batch transparency ledger publishes purity per release. Bulk discounts at three+; members save 25% plus free U.S. shipping for 365 days.

For research and laboratory use only. This product is not a drug, food, or cosmetic, and is not intended for diagnostic, therapeutic, or in vivo human use.